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Taking a pathological approach to evolving AI

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30th October, 2024

Science fiction doesn’t stay fiction for long these days, and in applying artificial intelligence (AI) and augmented intelligence applications in pathology we seem destined for the same.

Har­ness­ing AI to keep improv­ing our ser­vices and relieve staff from some of the tedious but nec­es­sary grunt work in our oper­a­tions is high on NSW Health Pathology’s (NSWHP) list of pri­or­i­ties, but it’s a care­ful jour­ney we are on to dis­cov­er what’s pos­si­ble with­out pos­ing risks.

NSWHP Chief Infor­ma­tion Offi­cer James Pat­ter­son says patient safe­ty and the high secu­ri­ty of sen­si­tive patient, foren­sic and sci­en­tif­ic data we admin­is­ter is para­mount when con­sid­er­ing what AI could offer.

“We’re at a point where we are assess­ing our organisation’s appetite for AI appli­ca­tions in pathol­o­gy,” James says.

“In some clin­i­cal set­tings it can rapid­ly speed up and fine-tune the diag­nos­tic process and pro­vide faster treat­ment for patients – mov­ing us fur­ther toward pre­ci­sion medicine.

“A good exam­ple of this is rapid AI review of thou­sands of tis­sue sam­ple slides and their com­par­i­son with new­ly arrived spec­i­mens to deter­mine if malig­nan­cy is present, there­by enabling anatom­i­cal pathol­o­gists to make faster diagnosis.”

Accu­rate diag­no­sis and treat­ment of genet­ic dis­or­ders could become faster as well, where AI is used to match phys­i­cal attrib­ut­es or phe­no­typ­ic traits often asso­ci­at­ed with spe­cif­ic genes.

It could also be a read­i­ly avail­able tool to assist in diag­no­sis that goes beyond our cur­rent reliance on human phe­no­typ­ic expertise.

“AI may sug­gest spe­cif­ic genet­ic tests to clin­i­cians soon­er based on phe­no­typ­ic traits that are present and avoid instances of unnec­es­sary test­ing. Ulti­mate­ly the patient ben­e­fits soon­er by get­ting the right treat­ments,” James says.

“At the moment, AI comes with plus­es and minus­es. It can save time and effort by min­ing our online store of knowl­edge. But emerg­ing gen­er­a­tions of pro­fes­sion­als will still need to accrue their own knowl­edge and exper­tise through prac­tice to ensure the pro­fes­sions don’t stag­nate and human curios­i­ty and cre­ativ­i­ty keeps being renewed.

“For now, in pathol­o­gy we are just dip­ping our toes into AI. We’re focus­ing main­ly on how it could help us in non-clin­i­cal set­tings such as in billing, or in pro­duc­ing reports drawn from data we accrue, to inform how we could do things bet­ter and plan strategically.”

Suran­ga Kas­turi who leads NSWHP’s Data and Insights team says safe ways of har­ness­ing gen­er­a­tive AI such as Chat GPT type mod­els were being explored to help clin­i­cians feel more com­fort­able using the emerg­ing technology.

“It’s a case of sup­port­ing cul­tur­al change by intro­duc­ing low-risk AI-dri­ven pro­ce­dures to our col­leagues who will have mixed expe­ri­ences work­ing with emerg­ing tech­nolo­gies and new ways of doing things,” Suran­ga said.

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