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COVID-19 results centre

COVID-19 results centre

In a NSW Health Pathology first, our COVID-19 Results Centre has provided a timely, empathic end-to-end customer experience during the once in 100 year pandemic.

They pro­vide a human touch when it’s most need­ed and lit­er­al­ly get results.

They build rap­port with our patients, con­fi­dence in our ser­vices, and pro­vide cer­tain­ty at times of great stress and wor­ry, let­ting peo­ple know when they can leave iso­la­tion to resume work, school and travel.

They’re the NSW Health Pathol­o­gy COVID-19 Results Ser­vice, and they’ve been named as final­ists for keep­ing peo­ple safe and healthy in the 2022 NSW Health Pathol­o­gy Awards.

The call cen­tre was cre­at­ed to build on the work of our COVID-19 Results Ser­vice, sup­port­ing demand for SMS and Result Por­tal noti­fi­ca­tions of neg­a­tive, pos­i­tive, oth­er and inde­ter­mi­nate results. Oper­a­tors inter­vene if auto­mat­ed noti­fi­ca­tions fail due to mis­matched infor­ma­tion, help patients use our result ser­vice and por­tal, and sup­port our lab­o­ra­to­ries and COVID-19 teams and oth­er partners.

They’re fix­ers, work­ing sev­en days a week so peo­ple could say per­son­al good­byes to loved ones or wel­come new babies. They’ve arranged test­ing on route to the air­port for a cou­ple whose spec­i­mens were not processed, so they did­n’t miss a flight to their daughter’s graduation.

They use trans­la­tion ser­vices to over­come lan­guage bar­ri­ers and relay results direct to patients with lit­tle or no Eng­lish. Those who are unfa­mil­iar with new com­mu­ni­ca­tions tech­nol­o­gy are patient­ly helped to reg­is­ter with our ser­vice and access their results.

Some­times they find patients alone and strug­gling in iso­la­tion with­out fam­i­ly and friends for sup­port. They lis­ten to their sto­ries, which makes a big dif­fer­ence to their day, and will sug­gest where to find support.

The team would like to acknowl­edge the efforts of its lab­o­ra­to­ry call cen­tre col­leagues and the army of NSW Health Pathol­o­gy vol­un­teers who helped staff our result ser­vice when it was first established.

New research could uncover genetic ticking time bomb for thousands of Australians with undiagnosed condition

A new research project is aiming to get more family GPs involved in genetic medicine, which researchers hope will help thousands of Australians with an undiagnosed lipid disorder that greatly increases their risk of cardiovascular disease.

Researchers at NSW Health Pathol­o­gy have been giv­en a grant to imple­ment a shared-care mod­el for scal­ing up genet­ic med­i­cine and get more fam­i­ly gen­er­al prac­ti­tion­ers involved in genetics.

The research will tar­get a con­di­tion that mas­sive­ly increas­es the risk of car­dio­vas­cu­lar disease.

Car­dio­vas­cu­lar dis­ease was the under­ly­ing cause of over 42,000 deaths in Aus­tralia in 2019. It was also behind the hos­pi­tal­i­sa­tion of 591,000 Aus­tralians in 2018–19, a stag­ger­ing 5.2% of all hospitalisations.

Chief Inves­ti­ga­tor, Asso­ciate Pro­fes­sor David Sul­li­van said the research will imple­ment a gen­er­al prac­tice and med­ical spe­cial­ist shared-care mod­el for genet­ic med­i­cine to improve the detec­tion of famil­ial hyper­c­ho­les­terolemia (FH).

“FH rep­re­sents an exem­plary Tier 1 con­di­tion for the imple­men­ta­tion and scal­ing of genet­ic med­i­cine,” A/Prof Sul­li­van said.

“Few­er than 10 per­cent of the more than 50,000 peo­ple in NSW at risk of FH have been iden­ti­fied, which is con­cern­ing as it increas­es their risk of car­dio­vas­cu­lar dis­ease by more than 100-fold in younger age groups.

“If untreat­ed, it advances the onset of car­dio­vas­cu­lar dis­ease by 20 to 40 years.”

While the ben­e­fits of detect­ing FH through genet­ic test­ing and cas­cade screen­ing are well estab­lished, the ide­al mod­el for imple­men­ta­tion at scale in Aus­tralia has not yet been established.

“FH is too com­mon to rely on ter­tiary refer­ral cen­tres to man­age all patients, espe­cial­ly for those with only rou­tine man­age­ment needs,” said A/Prof Sul­li­van. The research project will deter­mine how exist­ing ter­tiary health ser­vices can sup­port the deliv­ery of genet­ic med­i­cine at scale.

The project will assess the appro­pri­ate­ness and fea­si­bil­i­ty of the shared-care mod­el and a health eco­nom­ics study will be con­duct­ed, includ­ing mea­sur­ing the num­ber of peo­ple test­ed for and detect­ed with FH.

Researchers will be seek­ing to under­stand the bar­ri­ers and enablers to imple­men­ta­tion before tai­lor­ing the mod­el and imple­men­ta­tion strat­e­gy sup­port pack­age for local clin­i­cian and patient needs.

The research has been fund­ed under the NSW Trans­la­tion­al Research Grants Scheme which funds projects that will trans­late into bet­ter patient out­comes, health ser­vice deliv­ery, and pop­u­la­tion health and wellbeing.

Two towns, one goal

Our regional pathology labs have been working hard throughout the pandemic to protect the communities they call home. Two senior scientists from our Dubbo and Lismore laboratories discuss how the COVID-19 response transformed their working lives and what drew them to pathology.

They’re almost 800 kms apart, but two senior sci­en­tists lead­ing NSW Health Pathol­o­gy region­al lab­o­ra­to­ries have been on the front­line of the COVID-19 pan­dem­ic response to help pro­tect their local communities.

Sit­u­at­ed at the tail end of the Wilsons Riv­er in the North­ern Rivers region, sci­en­tists at NSW Health Pathology’s Lis­more lab­o­ra­to­ry are a wil­ful force of test­ing and analysis.

In 2020, the lab was test­ing the high­est num­ber of patient swabs out­side of its sis­ter lab­o­ra­to­ries in Syd­ney, turn­ing over about 300 to 400 COVID-19 diag­nos­tic tests a day.

At the helm was Senior Sci­en­tist and Micro­bi­ol­o­gy Lab Man­ag­er Glenn Hawkins.

Glenn leads a team of 10, made up of lab­o­ra­to­ry sci­en­tists and tech­ni­cians, work­ing day and night to deliv­er time­ly and accu­rate COVID-19 test results.

Sam­ples are received from col­lec­tion cen­tres as far south as Grafton, fur­ther inland and up to Tweed Heads.

With test­ing num­bers on the rise, Glenn sup­port­ed his team by prob­lem solv­ing any chal­lenges that arose , remain­ing hands on to sup­port the analy­sis of patient swabs and keep­ing a hap­py and uni­fied team work­ing at their peak.

Glenn start­ed his cur­rent role at NSW Health Pathol­o­gy in 2008, and pri­or to that was a senior sci­en­tist at Prince of Wales Lab­o­ra­to­ry, Rand­wick where he start­ed his train­ing in 1993.

“I have always enjoyed sci­ence and was for­tu­nate to get a start in micro­bi­ol­o­gy in Syd­ney after I fin­ished my degree,” Glenn said.

“I have loved the job ever since. I see pathol­o­gy as an inte­gral part of the front­line of the health sys­tem, even though it often oper­ates behind the scenes.

“My favourite part of this role as a lab­o­ra­to­ry man­ag­er is see­ing the fan­tas­tic team­work and ded­i­ca­tion the team has for deliv­er­ing time­ly COVID-19 results for the North­ern Rivers com­mu­ni­ty,” Glenn said.

Out west on the oth­er side of the Blue Moun­tains, is the town of Dubbo.

It is here that Monique Mintern heads up the local NSW Health Pathol­o­gy laboratory.

The Dub­bo lab, locat­ed at the heart of the Cen­tral West, has been test­ing COVID-19 sam­ples col­lect­ed from across a region com­pa­ra­ble to the size of some Aus­tralian states.

Monique says she was first inspired to pur­sue sci­ence as a career by her Year 8 sci­ence teacher who iden­ti­fied her pas­sion and tal­ent for science.

This led to a path­way into pathol­o­gy, and she was first intro­duced to the field dur­ing the ear­ly stages of her uni­ver­si­ty study.

Her career jour­ney has includ­ed her work­ing in Syd­ney, Dar­win, and Vic­to­ria pri­or to head­ing out to Dubbo.

“I am con­stant­ly amazed at the vital role pathol­o­gy plays in the day-to-day lives of so many peo­ple,” Monique said.

“It has evolved into a pow­er­ful tool used to deter­mine the health sta­tus of patients and is vital in ensur­ing patients receive the best treat­ment for their needs.

“I am excep­tion­al­ly pas­sion­ate about high qual­i­ty health­care ser­vices, par­tic­u­lar­ly in rur­al and region­al com­mu­ni­ties, as patients in these com­mu­ni­ties may be far from the facil­i­ties of met­ro­pol­i­tan sites, but their needs are no dif­fer­ent,” Monique explained.

“I believe we make a sig­nif­i­cant dif­fer­ence in the ser­vices we pro­vide to our com­mu­ni­ties, and I would­n’t want it any oth­er way”.

Monique says hav­ing local exper­tise and capa­bil­i­ties to diag­nose COVID-19 cas­es quick­ly was vital to pro­tect the com­mu­ni­ty and curb the spread of the virus.

Hueston…we have a solution

One of the hardest working ‘quiet achievers’ behind the incredible work at NSW Health Pathology during the COVID-19 pandemic was Dr Linda Hueston. She developed crucial tests to detect antibodies in blood that could determine whether a person has been infected with the COVID-19 virus.

NSW Health Pathol­o­gy has been described as ‘the qui­et achiev­ers dur­ing the pan­dem­ic, work­ing incred­i­bly hard behind the scenes’.

The state­ment couldn’t be more true for Dr Lin­da Hue­ston, Prin­ci­pal Hos­pi­tal Sci­en­tist and Chief Serol­o­gist at NSW Health Pathology’s West­mead laboratory.

When the rest of the coun­try was sweat­ing through the bar­be­ques and back­yard crick­et games that are syn­ony­mous with Aus­tralia Day, Dr Hue­ston spent the long week­end of Jan­u­ary 2020 hard at work in her laboratory.

She was work­ing on devel­op­ing three assays that could tell whether a per­son had been infect­ed pre­vi­ous­ly with the COVID-19 virus, based on the anti­bod­ies present in their blood.

She suc­ceed­ed.

Dr Hue­ston pio­neered the immuno­flu­o­res­cent serol­o­gy tests used in NSW to detect the spe­cif­ic anti­bod­ies the body cre­ates to fight the COVID-19 virus.

A pos­i­tive serol­o­gy result indi­cates the per­son had been infect­ed at one time, which can tell us if some­one was recent­ly infect­ed, even if they had recov­ered with­out being test­ed or were infect­ed with­out exhibit­ing any symptoms.

Serol­o­gy not only con­firms recent infec­tion, it can also be used poten­tial­ly to deter­mine immu­ni­ty, to deter­mine com­mu­ni­ty spread and find those peo­ple who were asymp­to­mati­cal­ly infected.

Dr Hueston’s team was the first to pro­duce and use the suite of immuno­flu­o­res­cent anti­body assays for the diag­no­sis of COVID-19 and the tests have now been used for thou­sands of patients.

They have assist­ed lab­o­ra­to­ries across Aus­tralia and in New Zealand with sero­log­ic diagnosis.

“I like puz­zles, under­stand­ing how things hap­pen and the ‘why’ of things,” said Dr Hueston.

“It is amaz­ing to see the work you do mak­ing a pos­i­tive dif­fer­ence to peo­ple and com­mu­ni­ties you’ll nev­er meet and who will nev­er meet you.

“My sci­ence super­pow­er is curios­i­ty and ingenuity.

“By con­sid­er­ing what would hap­pen under cer­tain cir­cum­stances and let­ting my mind play with pos­si­bil­i­ties, I’ve devel­oped assays used to diag­nose dis­ease in humans and animals.”

With a strong his­to­ry of suc­cess­ful test devel­op­ment and its trans­la­tion into rou­tine diag­nos­tic tests, Dr Hue­ston was recent­ly award­ed fund­ing under the NSW Health COVID-19 Research Grants to devel­op a suite of new tests that will improve rapid diag­no­sis of this disease.

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